Antidiabetic Effects of Metal Nanoparticles in Rodents

Marjan Assefi; Nadeem Kizilbash; Naila Mahmood; Sohila Nankali; A. Nankali; Gholamreza Abdi

doi:10.9734/bpi/capr/v6/3473B

Authors

Marjan Assefi University of North Carolina at Greensboro, Greensboro, NC 27403, USA.
Nadeem Kizilbash Department of Chemistry, Faculty of Physical Sciences, Quaid-i-Azam University, Islamabad- 45320, Pakistan.
Naila Mahmood Molecular Immunology Laboratory, Atta-ur-Rehman School of Applied Biosciences, National University of Science and Technology, Islamabad, Pakistan.
Sohila Nankali Northcentral University, San Diego, CA, USA.
A. Nankali Kermanshah University of Medical Sciences, Kermanshah, Iran.
Gholamreza Abdi Department of Biotechnology, Persian Gulf Research Institute, Bushehr, 75169, Iran.

DOI:

https://doi.org/10.9734/bpi/capr/v6/3473B

Keywords:

Diabetes mellitus, silver nanoparticles, glycogenesis, metabolism

Abstract

Many people suffer from Diabetes Mellitus all over the world. It is a metabolic disorder that results in high blood Glucose level and is a multi-factorial problem marked by hyperglycemia due to decreased Insulin production or increased Insulin resistance. The restorative effect of Zinc Oxide and Silver nanoparticles on Streptozotocin-induced diabetic rodents has been investigated by numerous studies. The metal nanoparticles play an important role in clinical and natural applications. Although, Silver is an important metal used by many metabolic processes, very little information is available about the effect of Silver or Silver nanoparticles (SNPs) on Glucose metabolism. The reported results by various studies reveal a decrease in blood Glucose level of diabetic rodents treated with ZnONPs, Silver nanoparticles (SNPs) and Insulin.

Antidiabetic Effects of Metal Nanoparticles in Rodents

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