Determination of Lipid Profile and Atherogenic Indices for Cardiovascular Disease Risk Based on Different Fish Consumption Habits

Authors

  • Chandravathani Devadawson Department of Zoology, Faculty of Science, Eastern University, Chenkalady, Sri Lanka.
  • Chamila Jayasinghe Department of Food Science and Technology, Faculty of Livestock, Fisheries and Nutrition, Wayamba University of Sri Lanka, Makandura, Gonawila, Sri Lanka.
  • Sivakanesan Ramiah Department of Biochemistry, Faculty of Medicine, University of Peradeniya, Sri Lanka.
  • Arulnithy Kanagasingam Cardiologist Unit, Teaching Hospital, Batticaloa, Sri Lanka.

DOI:

https://doi.org/10.9734/bpi/capr/v1/15611D

Keywords:

Cardiovascular diseases, lipid profile, fish consumption, Atherogenic indices

Abstract

Objective: Habitual consumption of moderate amounts of fish is associated with reduced mortality from cardiovascular disease (CVD). However, the beneficial effects of fish-enriched diet seem contradictory due to the oxidation susceptibility of the polyunsaturated fatty acids in them. The atherogenic index is an important tool to identify people with CVD risk. Lipid profile levels are favorably affected by certain fish consumption habits, thereby decreasing the risk of coronary heart diseases. The aim of this study was to evaluate the plasma lipid profile of healthy people with different fish consumption habits and to assess CVD risk using atherogenic indices.

Methods: Fasting blood samples were collected from healthy people for lipid profile estimations with an automated analyzer. Detailed information regarding physical and atherogenic parameters was collected from each participant.

Results: The CVD risk profiles showed varying level with the type of fish consumption. Total cholesterol, triglyceride (TG), and non-high-density lipoprotein (Non-HDL-C) varied significantly among the types of consumers (p<0.05), whereas the high-density lipoprotein cholesterol showed variation (p<0.001). TG/HDL showed the greater level in inland fish consumers. However, atherogenic coefficient and Castelli risk index-2 did not show significant variation among type of fish eating. Atherogenic indices were borderline “high risk” among all fish eaters including beef eating habits.

Conclusion: Fish and beef eaters had high risk among other inland and sea fish eaters. Non-HDL-cholesterol could be a marker for a serum lipid pattern associated with increased risk of heart diseases. All fish including beef eaters had a non- HDL-C level that was borderline high risk for CVD. TC and lipid-protein fractions had age- and sex-related differences. Women had higher TC and LDL-C levels than men. The values of non-HDL-C and TG/HDL-C can be used as improved diagnostic factors for CVD risk.

Published

2022-03-14

How to Cite

Chandravathani Devadawson, Chamila Jayasinghe, Sivakanesan Ramiah, & Arulnithy Kanagasingam. (2022). Determination of Lipid Profile and Atherogenic Indices for Cardiovascular Disease Risk Based on Different Fish Consumption Habits . Challenges and Advances in Pharmaceutical Research Vol. 1, 81–89. https://doi.org/10.9734/bpi/capr/v1/15611D