Kinetic Studies in the Oxidation of 2-aryl-3-Hydroxychromenones Using Sodium Hypochlorite (NaOCl) as an Oxidant

Authors

  • Kulvir Kaur Department of Chemistry, Punjabi University, Patiala, Pin Code- 147002, India.
  • Gurmeet Kaur Department of Chemistry, Punjabi University, Patiala, Pin Code- 147002, India.
  • Mandeep Kaur Department of Chemistry, Punjabi University, Patiala, Pin Code- 147002, India.
  • Amandeep Kaur Department of Chemistry, Punjabi University, Patiala, Pin Code- 147002, India.
  • Manisha Bansal Department of Chemistry, Punjabi University, Patiala, Pin Code- 147002, India.

DOI:

https://doi.org/10.9734/bpi/cacs/v8/15333D

Keywords:

3-hydroxy flavones, oxidizing agent, absorption spectra, dimeric product, kinetics

Abstract

Oxidation of 3-hydroxy flavone (3-HF) and 3-hydroxy-2-(thiophene-2-yl)-4H-chromen-4-one (THC) with sodium hypochlorite (NaOCl) as an oxidizing agent, has been reported. 3-hydroxy-2,3-dimethoxy-2-phenylchroman-4-one (1a) has been identified as the product of 3-HF in methanol (MeOH ) as solvent, by IR, 1H-NMR and ESI-MS spectroscopic techniques. This product is formed without any side reaction. Yield of this product is close to 100%, which could be calculated by separating the absorption spectra of the product from that of the reaction mixture in situ. On the other hand, by similar oxidation THC gives a dimeric product (2a). A mechanism for the formation of 1a has been given.

Published

2022-02-07

How to Cite

Kulvir Kaur, Gurmeet Kaur, Mandeep Kaur, Amandeep Kaur, & Manisha Bansal. (2022). Kinetic Studies in the Oxidation of 2-aryl-3-Hydroxychromenones Using Sodium Hypochlorite (NaOCl) as an Oxidant. Challenges and Advances in Chemical Science Vol. 8, 59–69. https://doi.org/10.9734/bpi/cacs/v8/15333D

Issue

Challenges and Advances in Chemical Science Vol. 8

Section

Chapters