Determining the Properties of Phenobarbital an Antiepileptic Drug Using Chemcalise Software
DOI:
https://doi.org/10.9734/bpi/cacs/v6/5051FKeywords:
Phenobarbital, properties, pka, isoelectric point, logP, logD, solubility, geometry, HNMRAbstract
Medications of barbiturate class are used in the treatment of certain types of diseases like insomnia (difficulty sleeping), and for controlling certain seizures. One such type of medicinally important compound is Phenobarbital. It is also known for its activities as anticonvulsant, antidepressant and antihypnotic [1]. Phenobarbital is used for treatment of seizures and its structure is studied with the objective of making the drug available at affordable prize, wide range of action and convenience of use. With these advantages it is considered to be a most efficient antiepileptic drug and is used as nonselective central nervous system depressant. In view of medicinal importance of Phenobarbital [1-3]. Its structure and properties were studied by using chemcalise softwareof Chemaxon and data obtained is interpreted.