Effect of Insect Tea on Acute Gastric Injury

Authors

  • Xin Zhao Chongqing Collaborative Innovation Center for Functional Food, Chongqing University of Education, Chongqing 400067, China and Chongqing Engineering Research Center of Functional Food, Chongqing University of Education, Chongqing 400067, China and Chongqing Engineering Laboratory for Research and Development of Functional Food, Chongqing University of Education, Chongqing 400067, China and Department of Food Quality and Safety, Chongqing University of Education, Chongqing 400067, China.
  • Qiang Cheng School of Public Health, Guilin Medical University, Guilin, Guangxi, 541004, China and Institute of Preventive Medicine, Guilin Medical University, Guilin, Guangxi, 541004, China.
  • Yu Qian Chongqing Engineering Laboratory for Research and Development of Functional Food, Chongqing University of Education, Chongqing 400067, China and Department of Food Quality and Safety, Chongqing University of Education, Chongqing 400067, China and School of Public Health, Guilin Medical University, Guilin, Guangxi, 541004, China and Institute of Preventive Medicine, Guilin Medical University, Guilin, Guangxi, 541004, China.
  • Ruokun Yi Chongqing Engineering Laboratory for Research and Development of Functional Food, Chongqing University of Education, Chongqing 400067, China and Department of Food Quality and Safety, Chongqing University of Education, Chongqing 400067, China and School of Public Health, Guilin Medical University, Guilin, Guangxi, 541004, China and Institute of Preventive Medicine, Guilin Medical University, Guilin, Guangxi, 541004, China.
  • Lianjie Gu Chongqing Collaborative Innovation Center for Functional Food, Chongqing University of Education, Chongqing 400067, China.
  • Shanshan Wang Chongqing Collaborative Innovation Center for Functional Food, Chongqing University of Education, Chongqing 400067, China.
  • Jia-Le Song Chongqing Collaborative Innovation Center for Functional Food, Chongqing University of Education, Chongqing 400067, China and School of Public Health, Guilin Medical University, Guilin, Guangxi, 541004, China and Institute of Preventive Medicine, Guilin Medical University, Guilin, Guangxi, 541004, China.

Keywords:

Insect tea, mice, acute gastric injury, expression

Abstract

Our goal of this chapter was to determine the protective effects of insect tea against hydrochloric acid/ethanol induced gastric ulcers in mice. Using a commercial kit for serum determination and Western blot for gastric tissue determination, insect tea reduced hydrochloric acid/ethanol induced gastric secretion and increased gastric pH. Insect tea increased vasoactive intestinal peptide and somatostatin levels and decreased serum motilin, substance P, and endothelin levels. Insect tea increased gastric superoxide dismutase and nitric oxide levels and decreased malondialdehyde levels in the gastric ulcer model mice. Gastric expression of NF-kB, EGF, EGFR, nNOS, eNOS, Mn-SOD, Cu/Zn-SOD, and CAT were increased in insect tea treated mice compared to untreated model mice. NF-kB and iNOS decreased in mice treated with insect tea compared with untreated model mice. Based on the present findings, insect tea appears to protect ICR mice from hydrochloric acid/ethanol induced gastric ulcers.

Published

2021-05-06

How to Cite

Xin Zhao, Qiang Cheng, Yu Qian, Ruokun Yi, Lianjie Gu, Shanshan Wang, & Jia-Le Song. (2021). Effect of Insect Tea on Acute Gastric Injury. Bioactivity of Chinese Insect Tea, 3–15. Retrieved from https://stm.bookpi.org/BCIT/article/view/951

Issue

Bioactivity of Chinese Insect Tea

Section

Content