WGS: An Innovative Approach for Management of Tuberculosis

Abstract

Whole genome sequencing (WGS) of Mycobacterium tuberculosis is becoming a promising tool for clinical applications for the diagnosis and management of tuberculosis in public health care. Since absence of a consensus and international standards in the analysis and validation of quality controlling of WGS technology, result may lack harmonization and comparability for diagnosis. In this review, the significance of WGS in diagnosis and surveillance is outlined.