Recent Advances in Nanoemulsion for Drug Delivery
Advanced Concepts in Pharmaceutical Research Vol. 5,
30 January 2024
,
Page 11-20
https://doi.org/10.9734/bpi/acpr/v5/8547A
Abstract
Submicron-sized emulsions known as nanoemulsions (NE) are being studied in great detail as drug carriers to enhance the delivery of therapeutic agents. With the use of the proper surfactants, two immiscible liquids (oil and water) are combined to form a single phase in NEs, which are thermodynamically stable isotropic systems. Nanoemulsions are stable against creaming or sedimentation because of their small droplet size; the primary mechanism of nanoemulsion breakdown is Ostwald ripening. The typical range of nanoemulsion droplet sizes is 20–200 nm. The size and surface characteristics of the nanoemulsion's droplets have a significant impact on how the formulation behaves biologically. Future developments in drug therapy, cosmetics, diagnostics, and biotechnologies appear to be greatly enhanced by nanoemulsion.
- NE
- Microfluidization
- sedimentation
- droplets