Concomitant Cases of Primary Biliary Cholangitis and Immune Thrombocytopenia

Authors

  • Toru Shizuma Department of Physiology, Tokai University School of Medicine, 143, Shimokasuya, Isehara, Kanagawa 259-1193, Japan.

DOI:

https://doi.org/10.9734/bpi/acmmr/v3/6463B

Keywords:

Primary biliary cholangitis, immune thrombocytopenia, Evans syndrome, autoimmune hemolytic anemia, autoimmune hepatitis

Abstract

Background: Although autoimmune diseases are often concomitant, the coexistence of primary biliary cholangitis (PBC) and immune thrombocytopenia (ITP) is rare.

Aim of Study: In this study, cases with concomitant PBC and ITP, including cases of Evans syndrome, were reviewed.

Methods: A literature search on scientific articles in English was conducted using the PubMed database, regarding the coexistence of PBC and ITP.

Results and Conclusion: Among the 20 cases, PBC was diagnosed first in 6 cases and ITP in 2 cases, while both diseases were almost simultaneously diagnosed in the remaining 12 cases. Standard pharmacotherapies of ursodeoxycholic acid and corticosteroids were used for concomitant cases. Of these cases, fatality was reported in 1 case.

Published

2023-11-03

How to Cite

Toru Shizuma. (2023). Concomitant Cases of Primary Biliary Cholangitis and Immune Thrombocytopenia. Advanced Concepts in Medicine and Medical Research Vol. 3, 68–77. https://doi.org/10.9734/bpi/acmmr/v3/6463B